Jos A.W.M Corver – Netherlands

Ana Bacaoanu Ph.D., eng. – Romania


Born: Buruienesti, district Neamt, January 17, 1947, Romania
Home address: Str. Sf. Lazar, no.49, Sc. A3, ap. 9, Iasi 6600, Romania
Home phone: +40-(0) 32-230939


1970 “Gh.Asachi” Technical University of Iasi, Faculty of Industrial Chemistry, Specialty Technologies of Macromolecular Compounds

1992 Degree: Ph.D. in Chemical Engineering.

Thesis title: “Drying of materials by direct contact with a heated surface”

Present position

Associate professor in Department of Chemical Engineering, Technical “Gh. Asachi” University of Iasi, Romania

As associate professor, I am presently involved in the following undergraduate courses:

At Technical University of Iasi:

Transport phenomena and unit operations in chemical industry
Intensification of transport phenomena
Unit operations with mass transfer
Project Engineering of Process Plants
Drying of materials course for Master degree

At Technical College of Iasi: Unit operations in chemical industry

I am also supervising about 3-4 Master students a year

My main course, “Transport phenomena and unit operations in chemical industry” contains the theory of transport of momentum, heat and mass transfer applied to a large number of chemical engineering applications. The general idea is to try to model the industrial processes based on the physical phenomena occurring. As the process is broken down into smaller processes and smaller details, the phenomena can to a large extent be described by fundamental equations and existing empirical correlations. This involves detailed knowledge (both modeling and experimental) about transport process on a molecular level in different materials.

I possess fundamental and general knowledge in the chemical and food industry. This background allows me to undertake various problems.

Main professional interests

Heat transfer

Heat transfer is probably the most common unit operation within chemical as well within food processing industries. The control of the flow of heat at desired rate is of prime importance in the design and operation of the heat transfer equipment in the processing industry.


My main contribution in the science is referring to the drying operation. My doctoral thesis treats the procedure used for drying of materials by direct contact with a heated surface. The physical model of drying and the mechanism have been elaborated.

I have a special interest for Lyophilization (Freeze-Drying). For couple of years, I have a rewarding collaboration with Thomas A. Jennings Ph.D., Chairman of International Society of Lyophilization – Freeze Drying, regard to the mechanism of freeze-drying and steam sterilization of dryers.

As visiting scientist at University of Karlstad, Sweden, I took part in the study of wood fuel (chips) drying in a pilot plant using superheated steam as medium drying.

Also, in the Department of Chemical Engineering, University of Iasi, I studied the drying in a fix bed, fluidized or vibrato-fluidized bed as well as spouted bed of different materials.

Other activities

I have been responsible for different activities to develop the graduate studies in various ways (graduate courses, information materials). I am an active member of Chemical Engineering Society from Romania.

I am an author of scientific papers, patents, books and research contracts with various chemical enterprises.

Selective Publications

Ana Bacaoanu, A General Discussion of Steam Sterilization of Freeze Dryers, European Pharmaceutical Review, 5, (1), 2000, pp. 40-43
Ana Bacaoanu, Thomas A. Jennings, Steam Sterilization of Freeze-Dryers – Dead Legs, European Pharmaceutical Review, 5, (3), 2000, pp.27-30
Ana Bacaoanu, Superheated Steam- Medium Drying, Romanian Chemical Quarterly Reviews, 7 (4), 1999, pp.307-316
Ana Bacaoanu, Radu Z. Tudose, Drying of Solid Materials by Direct Contact with a Heated Surface. Modeling of Constant Drying rate Period, Hungarian Journal of Industrial Chemistry, 25 (1), 1997, pp.53-58
Ana Bacaoanu, Radu Z. Tudose, Sechage des materiaux solides par contact direct avec une surface chauffe. VII. Modelage mathematique du stade a vitesse decroissante, Revue Roumaine de Chemie, 39 (11), 1994, pp. 1257-1266
Ana Bacaoanu, Radu Z. Tudose, Drying of materials by direct contact with a heated surface. VI. Critical moisture. Revista de Chimie, 47 (6), 1996, pp. 559-563.
Ana Bacaoanu, Radu Z. Tudose, Drying of materials by direct contact with a heated surface. II. Modeling of the stage of material heating, Revista de chimie, 43 (3-4), 1992, pp.147-154
Ana Bacaoanu, Radu Z. Tudose, Drying of materials by direct contact with a heated surface. I. Diffussion of water vapor through grain beds, Materiale plastice, 27, (3), 1990, pp.147-150
Radu Z. Tudose, Ana Bacaoanu, Experimental studies on the drying of powered polyvinyl chloride. II. Optimization of drying in vibrofluidizede bed, Materiale plastice, 24 (1), 1987, pp. 44-49
Radu Z. Tudose, Ioan Ibanescu, Florin Vitan, Ana Bacaoanu, Drying of materials in fix and fluidized bed, Celuloza si hartie, 36,(3),1987, pp.112-115

Apparatus for distilled water obtaining of high purity, Radu Z. Tudose, Ana Bacaoanu, RO PATENT 101073/1990.
Filling bodies for mass transfer columns, Radu Z. Tudose, Ana Bacaoanu, RSR PATENT 83269/20.10.1983
Heat accumulator, Radu Z, Tudose, Ana Bacaoanu, RSR PATENT 84473/1984
Apparatus for distilled water obtaining of high purity, Radu Z. Tudose, Ana Bacaoanu, RO PATENT 101073/1990.
Heat accumulator, Radu Z. Tudose, Liliana Horoba, Ana Bacaoanu, RSR PATENT 87861/1985

Transport Phenomena and Equipment in Chemical Industry Guide for laboratory works, R. Z. Tudose, I. Ibanescu, A. Bacaoanu, Iasi, IPI, 1985
Transport Phenomena and Equipment in the Chemical Industry Guide for year project, R. Z. Tudose, I. Ibanescu, A. Bacaoanu, Iasi, IPI,1990
Unit Operations and Equipment in Chemical and Food Industry, Ana Bacaoanu, IPI Iasi, 1996

Susan Ríos – Peru


Dr. Paul Matejtschuk – UK

Dr. Enric Jo – Spain


Name: Dr. Enric Jo

Born: Barcelona, Spain. February, 13, 1959.

Professional data:

ReigJofre Group

Av. Gran Capitán nº 10

08970 Sant Joan Despí, Barcelona, Spain

Tel.: +34934806708

Fax: +34934806720

Mov: +34670054398


Home data:

Pº Colón 8, 2º

08002 Barcelona, Spain

Tel.: +34933101415

Fax: +34932954036

I obtained the Degree and PhD in Pharmacy from the University of Barcelona. I focussed my doctorate thesis on lyophilization processes. I worked at the Biopharmacy Department of the College of Pharmacy in Barcelona for 4 years. Since 1993 I have been working at Reig Jofré Group, where nowadays I’m Plant Manager in Barcelona site and responsible for the Center of Excellence in Lyophilization. I worked as GMP Adviser for the Inspection Service of the AEMPS for four years and, nowadays, I’m coach for aseptic and freeze drying processes to the Spanish Healthcare Agency. At present, I collaborate on the ISL-FD, and I’m an active partner of associations as PDA and ISPE.

Communications and courses related with Freeze Drying:

AEMPS: Technical and Regulatory Aspects. AEMPS. Madrid, 16th December 2010.

iiR Spain: Manufacturing of Sterile Medicines. Work Shop (2nd Ed). Barcelona, 3rd – 4th, November 2010.

PDA Workshop. 2010 Pharmaceutical Freeze Drying. San Diego (CA) US. “First Aproach Appliying QbD in a Scale up of a Lyophilization Cycle for an Antiviral Product”.17th – 18th Nov 2010.

VISIONGAIN, 3th Annual Lyophilisation: Ensuring Optimum Formulations for Pharmaceuticals and Biologicals: “Main Manufacturing Challenges in a Lyophilization Processes”In Boston, MA (US); 23rd -25th February 2010.

A3P: 22e Congrès International A3P: “Procédé de Lyophilisation: Succès dans le Scale-up”. Biarritz, 20-22 Octubre 2009.

VISIONGAIN, 2nd Annual Lyophilisation. Panel Discussion: State of art in Lyophilization Technology in London, 15th-17th September 2009 at BSG Conference center.

PALL Europe. Jornadas Técnicas; “Aplicación de procesos de filtración esterilizante bajo la perspectiva del PDA Technical Report nº 26”.Madrid: 5 de mayo 2009, Barcelona: 7 mayo 2009.

IMA-Edwards: ”General Insight on Issues Related with Freeze Drying Processes in Industrial Manufacturing”.In Barcelona, 16th April 2009.

PDA Europe, Interest Group Meeting: Freeze Drying: “Suggestions to define a working structure in the European Interest Group of Freeze Drying”.Frankfurt on 2 April 2009 at the Sheraton Offenbach Hotel Am Büsing Palais I Berliner Str.111 – 63065 Offenbach

iiR Spain: Manufacturing of Sterile Medicines. Work Shop (1st Ed). Barcelona, 3rd – 4th, November 2009.

Institut Catala de la Salut: “Els nous requeriments en la fabricació de medicaments estèrils-EMEA – Annex 1”. 6ª Jornada de Normes de Correcta Fabricació de Medicaments. Barcelona, Spain. 11 Desembre 2008.

ISPE: “Parameter Characterization of a Lyophilization Cycle”. 2008 ISPE Conference on Applying a Science and Risk-based Approach. Barcelona, Spain, 1st-4th December 2008.

PDA Europe: “Parameter Characterization of a Lyophilization Cycle”. 2008 PDA Pharmaceutical Freeze Drying Technology. Wavre, Belgium, 23th-24th September 2008.


PMPS Manufacturing-Nov 2010, p 62: “Guaranteeing a Quality Scale-up”. Author: E Jo.

Pharmaceutical Technology – March 2010: “Thermal Fingerprinting and its application in the successful development and optimisation of Lyophilisation processes”. Vol 22. Nº 3. Pg 26-28.

PMPS Manufacturing-August 2009, p.46: “Freeze-Drying in Pharma”. Authors: J.Sassone; E. Jo; L. Noguera; JR.Mullick.

Dr. Jorge Sassone – Brazil